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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
17.27
Human Site:
Y230
Identified Species:
29.23
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
Y230
P
G
F
S
D
Q
V
Y
R
Q
R
R
K
L
I
Chimpanzee
Pan troglodytes
XP_508221
618
67613
Y320
P
G
F
S
D
Q
V
Y
R
Q
R
R
K
L
I
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
Y203
D
V
A
M
G
Y
K
Y
G
Q
P
I
P
R
V
Dog
Lupus familis
XP_855547
495
55650
I207
R
R
K
L
I
A
E
I
A
F
Q
Y
K
H
G
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
I207
Y
R
Q
R
R
K
L
I
A
E
I
A
F
Q
Y
Rat
Rattus norvegicus
P04177
498
55948
L206
V
Y
R
Q
R
R
K
L
I
A
E
I
A
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
Y270
P
G
F
K
D
P
V
Y
R
A
R
R
K
Q
F
Chicken
Gallus gallus
P70080
445
51121
H158
D
L
A
M
N
Y
K
H
G
D
P
I
P
E
I
Frog
Xenopus laevis
Q92142
481
55388
Y194
D
V
A
M
S
Y
K
Y
G
D
P
I
P
H
I
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
A202
R
K
M
I
G
D
I
A
F
K
Y
R
H
G
E
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
R189
F
I
A
E
L
A
S
R
Y
K
Q
G
D
P
L
Fruit Fly
Dros. melanogaster
P18459
579
65977
Y278
P
G
F
A
D
K
V
Y
R
Q
R
R
K
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
H170
D
I
A
F
N
F
K
H
G
D
K
I
P
T
I
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
Y224
P
G
F
T
D
K
D
Y
R
E
R
R
Q
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
13.3
6.6
N.A.
0
0
N.A.
66.6
6.6
13.3
6.6
0
80
N.A.
6.6
60
P-Site Similarity:
100
100
20
13.3
N.A.
20
6.6
N.A.
66.6
20
13.3
20
20
93.3
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
8
0
15
0
8
15
15
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
0
0
36
8
8
0
0
22
0
0
8
0
0
% D
% Glu:
0
0
0
8
0
0
8
0
0
15
8
0
0
15
8
% E
% Phe:
8
0
36
8
0
8
0
0
8
8
0
0
8
8
8
% F
% Gly:
0
36
0
0
15
0
0
0
29
0
0
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
8
15
0
% H
% Ile:
0
15
0
8
8
0
8
15
8
0
8
36
0
0
50
% I
% Lys:
0
8
8
8
0
22
36
0
0
15
8
0
36
0
0
% K
% Leu:
0
8
0
8
8
0
8
8
0
0
0
0
0
15
8
% L
% Met:
0
0
8
22
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
36
0
0
0
0
8
0
0
0
0
22
0
29
8
0
% P
% Gln:
0
0
8
8
0
15
0
0
0
29
15
0
8
15
8
% Q
% Arg:
15
15
8
8
15
8
0
8
36
0
36
43
0
15
0
% R
% Ser:
0
0
0
15
8
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
8
15
0
0
0
0
29
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
22
0
50
8
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _